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Nucleocapsid protein

Brief Information

Name:Nucleocapsid proteins
Target Synonym:Nucleocapsid Proteins
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
RAS-T184 SARS-CoV-2 Mouse Anti-SARS-CoV-2 (BA.1) Antibody IgG Titer Serologic Assay Kit (Nucleocapsid Protein)
NUN-M507 Human Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 (Trehalose free) (MALS verified)
NUN-M507-sds
NUN-C52Hw SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein, His Tag (BA.4/Omicron)
NUN-C52Hw-sds
NUN-C52Hx SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein, His Tag (BQ.1/Omicron)
NUN-C52Hx-sds
NUN-C82E9 SARS-CoV-2 Biotinylated SARS-CoV-2 Nucleocapsid protein, His,Avitag™ (BA.2*&BA.3*/Omicron)
NUN-C82E9-sds
NUN-C52Hv SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein, His Tag (BA.3*(S33V)/Omicron)
NUN-C52Hv-sds
NUN-CH14 Human Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (AS95) (MALS verified)
NUN-CH14-sds
NUN-CH15 Mouse Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) (MALS verified)
NUN-CH15-sds
NUN-C52Hu SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein, His Tag (BA.2*&BA.3*/Omicron)
NUN-C52Hu-sds
NUN-BM272 Mouse Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (AM223) (MALS verified)
NUN-BM272-sds
NUN-C52Ht SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron)
NUN-C52Ht-sds
NUN-C52Ha SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag
NUN-C52Ha-sds
NUN-C52Hr SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (D63G, R203M, G215C, D377Y), His Tag
NUN-C52Hr-structure
NUN-C52Hr-sds
NUN-C52Hs SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (D63G, R203M, D377Y), His Tag
NUN-C52Hs-structure
NUN-C52Hs-sds
NUN-C52Hp SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (D63G, R203M, D377Y, R385K), His Tag
NUN-C52Hp-structure
NUN-C52Hp-sds
NUN-C52Hn SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (R203M, D377Y), His Tag
NUN-C52Hn-structure
NUN-C52Hn-sds
NUN-C5145 SARS-CoV-2 SARS-CoV-2 Nucleocapsid Protein CTD, His Tag (MALS verified)
NUN-C5145-structure
NUN-C5145-sds
NUN-C5143 SARS-CoV-2 SARS-CoV-2 Nucleocapsid Protein NTD, His Tag (MALS verified)
NUN-C5143-structure
NUN-C5143-sds
RAS-A010 SARS-CoV-2 SARS-CoV-2 Nucleocapsid Protein Titer Assay Kit
RAS-T008 SARS-CoV-2 Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Nucleocapsid Protein)
NUN-C52Hd SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (T205I), His Tag
NUN-C52Hd-structure
NUN-C52Hd-sds
NUN-C52Hc SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (P80R), His Tag
NUN-C52Hc-structure
NUN-C52Hc-sds
NUN-C52Hg SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag
NUN-C52Hg-structure
NUN-C52Hg-sds
NUN-C52H8 SARS-CoV-2 SARS-CoV-2 Nucleocapsid protein (D3L, R203K, G204R, S235F), His Tag
NUN-C52H8-structure
NUN-C52H8-sds
NUN-S47L8 Mouse Biotinylated Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47)
NUN-S47L8-sds
MBS-K017 SARS-CoV-2 SARS-CoV-2 Nucleocapsid Protein-coupled Magnetic Beads
NUN-V5147 HCoV-229E HCoV-229E Nucleocapsid protein, His Tag
NUN-V5147-structure
NUN-V5147-sds
NUN-V5145 HCoV-OC43 HCoV-OC43 Nucleocapsid protein, His Tag
NUN-V5145-structure
NUN-V5145-sds
NUN-V5146 HCoV-NL63 HCoV-NL63 Nucleocapsid protein, His Tag
NUN-V5146-structure
NUN-V5146-sds
NUN-C82E8 SARS-CoV-2 Biotinylated SARS-CoV-2 (COVID-19) Nucleocapsid protein, His,Avitag™
NUN-C82E8-structure
NUN-C82E8-sds
NUN-S5229 SARS SARS Nucleocapsid protein, His Tag
NUN-S5229-structure
NUN-S5229-sds
NUN-C51H2 SARS-CoV-2 SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
NUN-C51H2-sds
NUN-C5221 SARS-CoV-2 SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
NUN-C5221-sds
NUN-M52H5 MERS MERS Nucleocapsid protein, His Tag
NUN-M52H5-structure
NUN-M52H5-sds
NUN-S46 Mouse Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS46) (Trehalose free)
NUN-S46-sds
NUN-S47 Mouse Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (Trehalose free)
NUN-S47-sds
NUN-S41 Human Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (AS41)
NUN-S41-sds
NUN-C5227 SARS-CoV-2 SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
NUN-C5227-structure
NUN-C5227-sds
NUN-C81Q6 SARS-CoV-2 Biotinylated SARS-CoV-2 (COVID-19) Nucleocapsid protein, His,Avitag™
NUN-C81Q6-structure
NUN-C81Q6-sds
NUN-C51H9 SARS-CoV-2 SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
NUN-C51H9-structure
NUN-C51H9-sds
ACRO Quality

Part of Bioactivity data

NUN-C52Hw-ELISA
 Nucleocapsid protein ELISA

Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag (BA.4/Omicron) (Cat. No. NUN-C52Hw) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Nucleocapsid Antibody, Chimeric mAb, Human IgG1 (Cat. No. NUN-CH15) with a linear range of 0.1-2 ng/mL (QC tested).

NUN-M507-MALS-HPLC
Nucleocapsid protein MALS images

The purity of Anti-SARS-CoV-2 Nucleocapsid Antibody-A5134, Human IgG1 (Cat. No. NUN-M507) is more than 90% and the molecular weight of this protein is around 140-160 kDa verified by SEC-MALS.

Synonym Name

Nucleocapsid protein,NP,Protein N

Background

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
PF-07923567 RV-299; PF-07923567 Phase 1 Clinical Reviral Ltd Respiratory Syncytial Virus Infections Details
PF-07923567 RV-299; PF-07923567 Phase 1 Clinical Reviral Ltd Respiratory Syncytial Virus Infections Details

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